As of 2025, there are 155,354 physician groups across the United States, representing a major portion of the country’s healthcare delivery network. These groups include multi-specialty, single-specialty, and hospital-affiliated physician organizations that collectively influence patient care, referrals, and medical device purchases.
If you’re a healthcare marketer, pharmaceutical company, or medical technology provider, identifying the largest physician groups by state can dramatically improve your outreach accuracy and campaign ROI. Ampliz’s comprehensive database enables you to access verified, compliant, and up-to-date physician group contact data to target the right decision-makers.
We will explore how to identify the largest physician groups in US state and how to leverage tools like Ampliz Healthcare Sales Intelligence to find, connect with, and reach them for effective healthcare marketing campaigns.
Why Target Physician Groups in US by State?
Each US state has its own healthcare market dynamics, payer mix, and physician concentration. Targeting by state allows marketers to:
- Identify regional leaders in patient volume and specialties
- Customize campaigns for local healthcare regulations and payer models
- Improve B2B conversion rates by focusing on relevant medical practices
- Access accurate contact data for administrators, physicians, and executives
For example, states like California, Texas, Florida, and New York have the highest number of large physician groups, with many housing over 500+ affiliated physicians per organization.
Top States with the Largest Physician Groups in US
Here’s a quick look at some leading states and their physician group density:
| State | Approx. Number of Large Physician Groups | Notable Physician Groups |
|---|---|---|
| California | 11,772 | Kaiser Permanente Medical Group, Sutter Health |
| Texas | 12,842 | Baylor Scott & White Health, Texas Health Physicians Group |
| Florida | 13,342 | Orlando Health Physician Associates, HCA Florida Physicians |
| New York | 10,602 | Mount Sinai Physicians Group, NYU Langone Medical Associates |
| Illinois | 6,542 | Northwestern Medical Group, Advocate Medical Group |
| Pennsylvania | 6,050 | UPMC Physicians Group, Jefferson Health Medical Group |
| Ohio | 4,800 | Cleveland Clinic Physicians, OhioHealth Group |
| Georgia | 5,270 | Emory Healthcare, Piedmont Physicians Group |
| North Carolina | 4,320 | Atrium Health, Novant Health Medical Group |
| Massachusetts | 3,321 | Mass General Brigham, Beth Israel Lahey Health |
Data Source: Ampliz Healthcare Intelligence Platform, 2025.
The Importance of Targeting Large Physician Groups
Before diving into the methods for identifying and reaching the largest physician groups in USA, let’s first understand why targeting them is important for healthcare marketing:
- Market Reach: Large physician groups typically have a broad patient base and a wide geographical reach, making them a great resource for expanding your service offerings.
- Referral Networks: These physician groups often work within extensive referral networks. A relationship with them can create opportunities to tap into these networks and gain new patients.
- Influence in Healthcare: Larger practices, especially those with multiple specialties, tend to have more sway in the healthcare market. They influence both patient care decisions and regional healthcare trends.
- Growth Potential: Physician groups are often looking for innovative tools, services, and products that can improve patient outcomes, streamline operations, and enhance their practice. If you can cater to these needs, you’re in a great position to generate valuable leads.
How to Find the Largest Physician Groups in USA By State
To identify the largest physician groups in each state, you can take advantage of healthcare sales intelligence tools like Ampliz Healthcare Sales Intelligence. Ampliz provides comprehensive data on healthcare providers, including detailed information on physician groups, their specialties, and practice sizes across the U.S. Here’s how to use it:
1. Create a Targeted Search with Filters
Ampliz allows you to customize your search using filters like:
- Location: Narrow your search to specific states or regions.
- Practice Size: Identify large physician groups based on the number of physicians in a practice.
- Specialty: Focus on multi-specialty groups or specific specialties that align with your healthcare services.
- Practice Type: Filter by independent practices, hospital-owned groups, or academic medical centers.
With these filters, you can easily generate lists of the largest physician groups based on your specific criteria.
2. Utilize Data Segmentation for Marketing
Ampliz’s segmentation tools can help you further refine your list by factors such as:
- Revenue and Growth Metrics: Identify financially strong and rapidly growing physician groups.
- Engagement Metrics: Understand how active certain groups are in adopting new services or technologies.
- Contact Information: Ampliz provides direct contact details (email addresses, phone numbers, etc.), so you can outreach directly.
3. Research and Build Custom Lists
Once you’ve built your targeted list, you can conduct in-depth research on each group, examining their practice focus, patient demographic, and regional impact. This allows you to tailor your marketing messages and outreach strategies more effectively.
Reaching the Largest Physician Groups for Healthcare Marketing
After identifying the largest physician groups, the next step is crafting a strategic outreach campaign. Here’s how to go about it:
1. Personalize Your Outreach
Physician groups are often inundated with marketing pitches, so it’s essential to stand out. Personalization is key. Use the data from Ampliz to understand the specific needs and challenges of each group and craft a message that speaks directly to them. Highlight:
- How your service or product can enhance patient care.
- Ways to streamline their operations.
- Any cost-saving or efficiency benefits.
2. Use Multi-Channel Outreach
Effective marketing to physician groups requires a multi-channel approach:
- Email Marketing: Start with a well-crafted email campaign targeting key decision-makers within the group. Use personalization and data-driven insights to make your email stand out.
- Phone Calls: Follow up with a call to discuss how your services can help them. Be prepared with relevant information based on your research.
- Direct Mail: Consider sending brochures or informational packets that provide value, focusing on how your offering can impact their practice.
- Social Media and Networking: Leverage LinkedIn and other professional networks to connect with decision-makers and engage in conversations.
3. Focus on Building Long-Term Relationships
Physician groups are more likely to work with vendors they trust and have built relationships with. Rather than focusing solely on a one-time sale, focus on building long-term partnerships by providing value, offering consistent support, and maintaining open communication channels.
4. Offer Educational Content
Physician groups often appreciate educational resources that can help them improve their practice. Webinars, whitepapers, case studies, and blog posts showcasing your expertise can position your company as a thought leader and trustworthy partner.
List of Largest Physician Groups in USA By State
We listing some of the biggest physician groups in the US, based on practice size, revenue, and influence. This is a sample and may vary depending on the specific metrics used.
| State | Physician Group | Number of Physicians | Specialty Focus | Location |
|---|---|---|---|---|
| California | Sutter Health | 2,000+ | Multi-Specialty | Sacramento, CA |
| Texas | UT Southwestern Medical Group | 1,500+ | Multi-Specialty | Dallas, TX |
| Florida | Florida Health Care Plans | 1,200+ | Family Medicine, Pediatrics | Daytona Beach, FL |
| New York | Northwell Health | 2,000+ | Multi-Specialty | New York, NY |
| Illinois | Advocate Health Care | 1,400+ | Multi-Specialty | Chicago, IL |
| Ohio | Cleveland Clinic | 3,000+ | Cardiology, Oncology, Neurology | Cleveland, OH |
| Pennsylvania | UPMC Physician Services | 2,500+ | Multi-Specialty | Pittsburgh, PA |
| Michigan | Henry Ford Health | 1,800+ | Multi-Specialty | Detroit, MI |
| Georgia | Emory Healthcare | 1,600+ | Multi-Specialty | Atlanta, GA |
| North Carolina | Atrium Health | 1,200+ | Multi-Specialty | Charlotte, NC |
| Indiana | Ascension Medical Group | 4000+ | Multi-Specialty | Indiana |
| Arizona | Banner Health Network | 3000+ | – | Arizona |
| Kansas | HCA Midwest Physicians | 300+ | Family Practice | Overland Park, KS |
| North Dakota | ||||
| Alaska | Alaska Native Tribal Health Consortium | 300+ | Anchorage, AK, USA | |
| Arkansas | Arkansas Health Group | – | – | Little Rock |
| Colorado | Centura Health Physician Group | – | – | Centennia |
| Louisiana | Louisiana Internal Medicine & Pediatric Associates | – | – | Covington |
Note: The above list is based on available data and is not exhaustive. The numbers can change depending on the latest reports from healthcare organizations and physician directories.
Conclusion
The US healthcare system continues to evolve, with physician groups consolidating rapidly to improve patient care and efficiency. To stay competitive, marketers and vendors must align their outreach with the largest, most influential groups across states.
With Ampliz’s 155,354 strong physician group database, you can discover new opportunities, segment effectively, and maximize your marketing performance.
👉 Explore the full list of physician groups by state with Ampliz today and connect with the right healthcare professionals for your business.
Whether you’re selling a product, offering a service, or looking to build a partnership, understanding the dynamics of large physician groups can help you achieve your marketing goals more effectively.
FAQs – Biggest Physician Groups in USA
1. How many physician groups are there in the U.S.?
As of 2025, Ampliz reports 155,354 physician groups across the U.S., including both multi-specialty and single-specialty groups.
2. What are the largest physician groups in the U.S.?
Some of the largest physician groups include Kaiser Permanente Medical Group, Sutter Health, HCA Physicians, and Mount Sinai Physicians Group.
3. How can Ampliz help me find physician group data by state?
Ampliz provides a state-wise physician group database with verified contact details, specialties, and leadership information to optimize marketing and outreach.
4. Why is physician group data important for healthcare marketing?
Accurate data helps healthcare companies target decision-makers, improve personalization, and enhance conversion rates across medical practices.
5. Can I access contact emails and phone numbers of physician groups?
Yes, Ampliz offers verified contact information, including emails, direct dials, and executive details, for targeted and compliant outreach.



