Introduction: Why Oncology Physician Groups Matter More Than Ever in 2025
The rise in cancer diagnoses, new immunotherapies, and personalized medicine has propelled oncology into one of the most critical specialties in U.S. healthcare. With over 18 million cancer survivors in the U.S. as of 2025, the demand for oncology services continues to climb. Physician groups specializing in oncology are leading this fight — not only through treatment but also by driving research, clinical trials, and value-based care delivery.
For healthcare marketers, oncology physician groups represent a high-value target audience. These groups often influence multi-million dollar decisions involving drugs, medical devices, diagnostics, and treatment protocols. Marketing to them requires precision, relevance, and above all, accurate data.
In this guide, we list the Top 20 Oncology Physician Groups in the U.S., explain the broader landscape of oncology groups, and show you how to reach them effectively using Ampliz Healthcare Data Intelligence.
What Are Oncology Physician Groups?
Oncology physician groups are organized practices composed primarily of hematologists and oncologists who provide comprehensive cancer care. These groups may operate independently or be affiliated with major health systems, academic hospitals, or cancer institutes.
They play a vital role in:
- Administering chemotherapy, immunotherapy, and radiation
- Participating in clinical trials
- Managing cancer patients longitudinally across diagnosis, treatment, and survivorship
- Influencing formulary and purchasing decisions
Due to their size, patient volume, and specialized services, they are an essential segment for healthcare vendors — from biotech firms to diagnostic labs.
Top 20 Oncology Physician Groups in the US (2025)
Below is a curated list of the most prominent oncology groups based on physician count, national presence, affiliations, and influence.
| Rank | Group Name | Location (HQ) | No. of Oncologists | Affiliation | Data Set |
|---|---|---|---|---|---|
| 1 | The US Oncology Network | The Woodlands, TX | 1,500+ | McKesson | Access Now |
| 2 | Florida Cancer Specialists | Fort Myers, FL | 250+ | Independent | Access Now |
| 3 | Texas Oncology | Dallas, TX | 500+ | US Oncology Network | Access Now |
| 4 | Minnesota Oncology | Minneapolis, MN | 100+ | US Oncology Network | Access Now |
| 5 | New York Cancer & Blood Specialists | New York, NY | 120+ | OneOncology | Access Now |
| 6 | Tennessee Oncology | Nashville, TN | 90+ | OneOncology | Access Now |
| 7 | Rocky Mountain Cancer Centers | Denver, CO | 70+ | US Oncology Network | Access Now |
| 8 | Arizona Oncology | Tucson, AZ | 65+ | US Oncology Network | Access Now |
| 9 | Illinois Cancer Specialists | Chicago, IL | 60+ | US Oncology Network | Access Now |
| 10 | Dayton Physicians Network | Dayton, OH | 50+ | American Oncology Network | Access Now |
| 11 | Maryland Oncology Hematology | Columbia, MD | 60+ | American Oncology Network | Access Now |
| 12 | Utah Cancer Specialists | Salt Lake City, UT | 40+ | Independent | Access Now |
| 13 | Compass Oncology | Portland, OR | 40+ | US Oncology Network | Access Now |
| 14 | Willamette Valley Cancer Institute | Eugene, OR | 35+ | US Oncology Network | Access Now |
| 15 | Cancer Care Northwest | Spokane, WA | 30+ | Independent | Access Now |
| 16 | Northwest Medical Specialties | Tacoma, WA | 28+ | American Oncology Network | Access Now |
| 17 | Oncology Hematology Care (OHC) | Cincinnati, OH | 30+ | American Oncology Network | Access Now |
| 18 | Michiana Hematology Oncology | Mishawaka, IN | 25+ | Independent | Access Now |
| 19 | Cancer & Hematology Centers of Western Michigan | Grand Rapids, MI | 30+ | Independent | Access Now |
| 20 | Florida Cancer Affiliates | Ocala, FL | 25+ | US Oncology Network | Access Now |
How Many Oncology Physician Groups Are in the US?
As of 2025, there are approximately 2,000+ oncology physician groups operating across the United States. These include:
- Independent groups
- Academic-affiliated oncology practices
- Hospital-owned oncology departments
- National networks like US Oncology, OneOncology, and American Oncology Network
These groups range in size from small two-physician practices to nationwide networks with hundreds of oncologists. Many of them are part of larger purchasing organizations and clinical trial consortia, making them powerful players in product adoption decisions.
Why Oncology Physician Groups Are a Prime Marketing Target
1. High Prescribing Authority
Oncologists often control formularies for cancer drugs, biosimilars, and specialty therapies — making them decision-makers worth targeting.
2. Specialized Equipment Needs
From infusion pumps to imaging, oncology groups purchase high-cost diagnostic and therapeutic equipment regularly.
3. Central to Patient Navigation
These groups guide patients through all aspects of cancer care — making them central touchpoints for products related to care coordination, EMRs, and diagnostic testing.
4. Influence on Guidelines and Research
Many oncology groups participate in or lead clinical trials, giving them influence in shaping future treatment protocols.
5. Long-Term Patient Relationships
Oncology patients typically require ongoing care over months or years. That translates into longer-term relationships between physician groups and the products they use or recommend.
How to Market to Oncology Physician Groups Using Ampliz Healthcare Data
Effective marketing to oncology physician groups requires:
- Accurate contact data
- Understanding of affiliations and specialties
- Timely outreach campaigns
This is where Ampliz Healthcare Data Intelligence comes in.
Here’s how Ampliz helps you reach oncology groups:
Comprehensive Database
Access verified data of over 2,000 oncology groups and 15,000+ hematologists/oncologists.
Affiliation Insights
See whether a group is part of US Oncology, OneOncology, or AON — critical for navigating group purchasing decisions.
Detailed Contact Info
Get direct emails, phone numbers, and LinkedIn profiles of decision-makers like Medical Directors, Procurement Heads, and Practice Managers.
Advanced Filters
Segment your target list by:
- Group size
- Location
- Specialty (e.g., Breast Oncology, Hematology, Radiation Oncology)
- Ownership (Private vs Hospital-owned)
Integration Ready
Export data directly to your CRM or marketing automation platforms like Salesforce, HubSpot, and Marketo.
Conclusion: How to Engage Top Oncology Physician Groups with Precision
With over 2,000 oncology physician groups in the U.S., marketers face a vast — but complex — landscape. These groups are high-value targets due to their influence on treatment decisions, equipment purchases, and drug adoption.
To successfully market your healthcare product or service to these groups, you need accurate, real-time, and segmented data.
Ampliz Healthcare Data Intelligence empowers you to:
- Identify the right oncology groups
- Understand their structure and influence
- Reach decision-makers with precision
- Shorten your sales cycle and improve ROI
Whether you’re selling oncology-specific pharmaceuticals, infusion devices, EMR platforms, or diagnostics, Ampliz gives you the edge to market smarter and faster.
FAQs
1. What is the largest oncology physician group in the US?
The US Oncology Network is the largest, with over 1,500 affiliated oncologists across 20+ states.
2. How can I market to oncology physician groups?
Use data platforms like Ampliz to access decision-makers’ contact information and segment your outreach based on group size, affiliation, and geography.
3. Are most oncology groups hospital-owned?
Not all — many are part of independent networks or national alliances like OneOncology or AON.
4. How often do oncology groups purchase new equipment or drugs?
Oncology groups frequently evaluate and adopt new drugs, devices, and software due to rapid advancements in cancer care.
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