Introduction

The healthcare industry in Oklahoma has witnessed remarkable growth over the past decade. With increasing patient demand, technology adoption, and government funding, hospitals in the Sooner State have significantly expanded their capabilities and revenues. Among the numerous performance metrics, net patient revenue stands out as a critical financial indicator.

In this blog, we’ll dive into a data-backed list of top hospitals in Oklahoma by net patient revenue. This analysis will help healthcare vendors, marketers, and providers understand where the largest volumes and highest-value care are delivered in the state.

Whether you’re trying to assess market opportunities or plan your next B2B healthcare campaign, this list will give you insight into the highest earning hospitals in Oklahoma for 2025.

What is Net Patient Revenue and Why It Matters?

Net patient revenue (NPR) refers to the revenue a hospital earns from patient care services, after deducting contractual allowances, discounts, and bad debts. It is one of the most reliable indicators of a hospital’s financial health.

Unlike gross charges, which reflect billed amounts, NPR gives a realistic snapshot of actual collections. In healthcare analytics, it’s used to:

  • Rank hospitals by economic performance
  • Determine market share of health systems
  • Identify top revenue-generating hospitals in a region
  • Benchmark operational efficiency

For suppliers and vendors, targeting hospitals by net patient revenue means focusing on facilities that have both scale and spending power.

Overview of Oklahoma’s Hospital System

Oklahoma is home to over 160 hospitals, including general acute care hospitals, specialty hospitals, and rural critical access hospitals. The state’s healthcare system is dominated by a few major players, such as:

  • OU Health (University of Oklahoma)
  • INTEGRIS Health
  • Saint Francis Health System
  • SSM Health Oklahoma
  • Hillcrest HealthCare System

These networks manage multiple high-volume facilities and employ thousands of clinicians across the state.

Urban centers like Oklahoma City and Tulsa account for most of the top hospitals in Oklahoma by net patient revenue, thanks to their larger populations, advanced care services, and teaching affiliations.

Top 20 Hospitals in Oklahoma by Net Patient Revenue

Below is a list of the largest hospitals in Oklahoma by net patient revenue, based on the latest available financial data and institutional disclosures.

RankHospital NameLocationHealth SystemNet Patient Revenue (USD)Bed CountDataset
1OU Health – University of Oklahoma Med CenterOklahoma CityOU Health$1.6 Billion880Access Now
2Saint Francis HospitalTulsaSaint Francis Health$1.3 Billion1000+Access Now
3INTEGRIS Baptist Medical CenterOklahoma CityINTEGRIS Health$1.1 Billion650Access Now
4Hillcrest Medical CenterTulsaArdent Health/Hillcrest$950 Million620Access Now
5SSM Health St. Anthony HospitalOklahoma CitySSM Health$800 Million500Access Now
6Mercy Hospital Oklahoma CityOklahoma CityMercy$750 Million475Access Now
7Norman Regional HospitalNormanNorman Health System$650 Million324Access Now
8Ascension St. John Medical CenterTulsaAscension Health$630 Million595Access Now
9INTEGRIS Southwest Medical CenterOklahoma CityINTEGRIS Health$590 Million360Access Now
10Comanche County Memorial HospitalLawtonIndependent$480 Million283Access Now
11McAlester Regional Health CenterMcAlesterIndependent$400 Million170Access Now
12Stillwater Medical CenterStillwaterIndependent$390 Million117Access Now
13Duncan Regional HospitalDuncanIndependent$370 Million140Access Now
14Bailey Medical CenterOwassoArdent Health$350 Million73Access Now
15Mercy Hospital ArdmoreArdmoreMercy$330 Million190Access Now
16Integris Grove HospitalGroveINTEGRIS Health$310 Million62Access Now
17OU Health EdmondEdmondOU Health$300 Million72Access Now
18Muskogee Medical CenterMuskogeeIndependent$280 Million120Access Now
19Hillcrest Hospital SouthTulsaHillcrest/Ardent$260 Million180Access Now
20SSM Health St. Anthony ShawneeShawneeSSM Health$240 Million150Access Now

These hospitals not only have high patient volumes but also offer specialized care, advanced procedures, and comprehensive services—making them prime targets for healthcare service providers and product companies.

5. Trends in Oklahoma Hospital Revenues

Several patterns are shaping the financial performance of hospitals in Oklahoma:

✅ Urban Consolidation

Major systems like INTEGRIS, OU Health, and SSM continue to acquire or affiliate with smaller hospitals, increasing their net patient revenue through scale.

✅ Technology-Driven Revenue Growth

Investment in advanced imaging, robotics, and electronic health records (EHRs) are driving both efficiency and revenue per encounter.

✅ Medicaid Expansion Impact

Oklahoma expanded Medicaid in 2021, which resulted in more insured patients and improved hospital reimbursement—especially for rural hospitals.

✅ Telehealth Adoption

Virtual care is becoming a revenue stream for both urban and rural hospitals, especially post-pandemic.

6. Why This Data Matters for Healthcare Vendors and Marketers

Understanding which hospitals in Oklahoma make the most revenue gives B2B marketers a clear direction on where to focus their outreach. Here’s why it matters:

  • High revenue = Higher budgets for software, devices, staffing, and services
  • Centralized decision-making in large systems (e.g., OU Health) makes for efficient outreach
  • Opportunity to scale your solutions across multiple hospitals within a single network

If you’re selling anything from diagnostic equipment to EHR systems or staffing solutions, targeting the top 20 hospitals by NPR is a smart strategy.

7. How to Reach Decision Makers in These Hospitals

While identifying top hospitals is essential, the real challenge is reaching the right decision-makers within them.

That’s where Ampliz Healthcare Data Intelligence comes in.

Ampliz offers verified, actionable data on over:

  • 10 million+ hospital decision-makers
  • 7,000+ hospitals across the US
  • Specific insights on CEO, CFO, CMO, Director of Nursing, Procurement Heads, and more
  • Filter by revenue size, specialties, health system, or location (like Oklahoma)

With Ampliz, you can directly target the top-performing hospitals in Oklahoma, understand their organizational structure, and personalize your marketing campaigns effectively.

📊 Example:

Want to sell to OU Health or SSM Health Oklahoma? Ampliz lets you access the right contacts within their corporate and facility-level teams—without wasting time on gatekeepers.

Conclusion

As healthcare continues to evolve in Oklahoma, understanding where the money flows is key to business success. This list of the top hospitals in Oklahoma by net patient revenue provides valuable direction for vendors, service providers, and consultants targeting the healthcare space.

These institutions represent not only the best in care delivery but also the most lucrative opportunities for growth and partnerships.

If you’re ready to take the next step and reach decision-makers at these hospitals, leverage Ampliz Healthcare Data Intelligence. With comprehensive data, real-time updates, and verified contacts, Ampliz makes it easy to connect with the right people, at the right hospital, at the right time.