Largest Physician Groups in the United States

Last updated on April 8th, 2026

Physician groups are becoming increasingly popular in the United States, as they offer a number of advantages for both doctors and providers. Physician groups in the US provide doctors with a number of benefits, such as increased earning potential, greater job security, and access to more resources. For patients, physician groups offer the convenience of having all of their healthcare needs met in one place.

There are a number of different types of physician groups, including:

• Independent physician groups: These groups are made up of a group of doctors who are not affiliated with a hospital or other healthcare system.
• Hospital-employed physician groups: These groups are employed by a hospital or other healthcare system.
• Multi-specialty physician groups: These groups offer a variety of different medical specialties, such as primary care, cardiology, and oncology.

Why Understanding Large Physician Groups in the US is Critical

In the evolving healthcare industry, physician groups play a crucial role in delivering patient care, negotiating with insurers, and driving innovations in treatment. As healthcare becomes more integrated, large physician groups are becoming essential players, often forming networks that allow for better coordinated care across hospitals and outpatient facilities. Understanding these groups is key for healthcare marketers and businesses aiming to target the right professionals in their outreach efforts.

The Importance of This Data

This blog focuses on the largest physician groups in the United States, based on revenue, size, specialties, and geographic reach. This information is valuable for companies targeting healthcare professionals for B2B marketing, sales, or service offerings. Whether you’re a healthcare data provider, a marketing firm, or a medical equipment manufacturer, knowing the key players in the healthcare industry can help you optimize your outreach.

Understanding Physician Groups in the US

What Are Physician Groups?

A physician group is an organized network of doctors who share resources, administrative support, and sometimes ownership of healthcare facilities. These groups typically operate in outpatient settings or as part of hospital networks. They can range from small, independent practices to large organizations that include thousands of doctors across multiple specialties.

• Independent Physician Groups: These are usually smaller and owned by the physicians themselves. They typically have fewer than 100 physicians.
• Large Physician Groups: These are larger entities, sometimes part of integrated delivery networks (IDNs), with hundreds or thousands of doctors across multiple regions and specialties.

Why They Matter

Large physician groups matter because they have significant influence over healthcare delivery in their regions. They help streamline administrative tasks, reduce healthcare costs, and improve patient outcomes through coordinated care. These groups also control a substantial share of patient populations, making them highly sought after by pharmaceutical companies, medical device makers, and healthcare service providers.

Economic Impact

Largest physician groups in US also play an economic role in their communities, employing large numbers of healthcare workers, generating significant revenue, and providing vital healthcare services. As they continue to grow, they become even more critical in shaping national healthcare policies and trends.

The largest physician groups in the United States are:

Fig 1: Data is from the Ampliz Healthcare Intelligence product. The number of practices represents only those listed as “active” in our database as of April 2026.

These physician groups employ a large number of doctors and provide a wide range of healthcare services. They are also some of the most financially stable physician groups in the United States.

Methodology for Ranking

Data Sources

The data for this ranking was compiled using a combination of Ampliz’s proprietary healthcare data intelligence, government databases, and publicly available financial reports. We also included insights from reputable industry reports, such as those from the American Medical Association (AMA) and Healthcare Financial Management Association (HFMA).

Ranking Criteria

The following criteria were used to determine the top physician groups in US:

1. Number of Physicians: The total number of practicing physicians within the group.
2. Revenue: Annual revenue generated by the group, which indicates the financial health and operational scale of the organization.
3. Specialties: The diversity of medical specialties offered by the group, reflecting their ability to serve a wide patient base.
4. Geographic Reach: The geographic footprint of the group, whether they operate regionally, nationally, or internationally.
5. Patient Volume: The total number of patients treated annually, an indicator of the group’s scale and reach.

Key Insights for Healthcare Marketers

Targeting Large Physician Groups for Marketing

Understanding the largest physician groups allows marketers to focus their efforts on high-potential organizations that can drive significant business. By targeting these groups, marketers can connect with a large number of healthcare professionals who make critical decisions about medical products, services, and technologies.

Data-Driven Marketing Strategies

Data-driven marketing leverages insights from physician group data to segment audiences effectively and tailor marketing messages. For instance, marketers can target specific specialties or geographic areas where their products or services are most relevant. By integrating CRM tools with accurate physician data, healthcare marketers can increase the effectiveness of their campaigns, improving engagement rates and ROI.

Challenges to Consider

1. Regulatory Compliance: Be mindful of regulations like HIPAA (Health Insurance Portability and Accountability Act) when handling healthcare data.
2. Data Accuracy: Ensure that the data you’re using is up-to-date and verified, especially when reaching out to large physician groups with complex organizational structures.
3. Ethical Marketing: Ensure that your marketing tactics comply with ethical guidelines and avoid aggressive sales strategies that might harm patient care or tarnish the group’s reputation.

How to Find a Physician Group List of Doctors

Ampliz can be a valuable tool for finding physician group lists of doctors. Here’s how you can use it:

Access the Ampliz Healthcare Intelligence: Log in to your Ampliz account or visit our platform.

Utilize the Search Filters:

• Location: Enter your city, state, or zip code to find groups in your area.
• Specialty: Specify the type of physician group you’re looking for (e.g., primary care, cardiology, multi-specialty).
• Other criteria: You may be able to filter by other criteria like group practice members, hospital affiliations data, and more.

Review Search Results: Ampliz will display a list of physician groups that match your criteria. Review the information provided for each group, such as:

• Group name and contact information
• List of physicians within the group
• Specialties offered
• Insurance accepted
• Patient reviews and ratings

Compare and Select: Compare the different groups based on your needs and preferences. Consider factors like location, specialties, insurance coverage, and patient reviews.

Contact the Group: Once you’ve selected a top physicians group, contact them to schedule an appointment or inquire about their services and other marketing purposes.

Additional Tips for Using Ampliz:

• Save your searches: Save your search criteria for future reference or to easily refine your search.
• Utilize the mapping feature: Ampliz may offer a map view to help you visualize the locations of different groups.
• Read patient reviews: Pay attention to patient reviews to get insights into the quality of care and patient experience at each group.

By effectively using Ampliz’s search filters and features, you can efficiently find physician groups that meet your specific needs and preferences.

Conclusion

Physician groups are a valuable resource for both doctors and patients. They offer a number of benefits, such as increased earning potential, greater job security, and access to more resources for doctors. For patients, physician groups offer the convenience of having all of their healthcare needs met in one place. If you are looking for a physician group, there are a number of resources that you can use to find one that is right for you.

FAQs

Q1: What are the largest physician groups in the US by revenue?
The largest physician groups include Mayo Clinic, Meridian Behavioral healthcare INC, and University Physician Incorporated, with annual revenues in the billions.

Q2: How are physician groups ranked?
Physician groups are ranked based on factors such as the number of physicians, annual revenue, geographic reach, specialties, and patient volume.

Q3: How do I find contact information for the largest physician groups?
You can access detailed contact information for physician groups through platforms like Ampliz, which provides healthcare contact lists and segmentation tools.

Q4: What are the benefits of marketing to large physician groups?
Marketing to large physician groups offers access to a large patient base, increased decision-making power, and the opportunity to collaborate on large-scale healthcare initiatives.

Q5: Are there any ethical considerations when marketing to physician groups?
Yes, ethical marketing practices are critical. Ensure compliance with healthcare regulations (like HIPAA) and respect the privacy of patients and professionals.

Subbu

V. Subramanyam
Head of Product at Ampliz | Growth-focused B2B Leader

V. Subramanyam is a Head of Product at Ampliz with a strong focus on driving growth and innovation. As the Head of Product at Ampliz, I leads the development and strategic direction of cutting-edge solutions that empower businesses to leverage high-quality healthcare data for better decision-making. With years of experience in product management and leadership, I have deep industry knowledge with a customer-centric approach to deliver value-driven products that accelerate business success. And I am passionate about using data intelligence to transform businesses and create impactful outcomes.