Introduction

Gastroenterology is among the fastest-growing specialties in U.S. healthcare. With over 1,500 active gastroenterology physician group practices operating across the country, these groups are hubs for delivering endoscopy, diagnostic, treatment, and specialist care for GI diseases.

Why focus on the largest practices? These groups—such as Texas Digestive Disease Consultants and Gastro Health—operate hundreds of clinicians across multiple states. Targeting such large-scale organizations enables healthcare vendors to secure high-volume contracts, foster strategic partnerships, and streamline sales and marketing efforts into centralized physician networks.

In this post, we explore the 20 largest GI group practices by headcount, delve into the main challenges in accessing decision-makers, and discuss how Ampliz healthcare data intelligence can empower effective marketing outreach.

Top 20 Largest Gastroenterology Physician Group Practices in the US

RankGroup NamePhysiciansData Set
1Texas Digestive Disease Consultants (TX)556Access Now
2Gastro Health (FL)475Access Now
3Connecticut GI (CT)312Access Now
4The Oregon Clinic (OR)253Access Now
5US Digestive Health (PA)155Access Now
6Capital Digestive Care (MD)128Access Now
7Unio Specialty Care (CA)127Access Now
8Atlanta Gastroenterology Associates (GA)123Access Now
9Minnesota Gastroenterology (MN)99Access Now
10Gastroenterology Associates of SW Florida (FL)98Access Now
11Borland Groover (FL)87Access Now
12Digestive Health Associates of Texas (TX)82Access Now
13GI Alliance of Illinois (IL)80Access Now
14Gastroenterology Associates of New Jersey (NJ)80Access Now
15Arizona Digestive Health (AZ)76Access Now
16GI Alliance (National MSO footprint)700Access Now
17United Digestive (GA + multi-state MSO)129Access Now
18One GI (Mid‑South states MSO)110+Access Now
19Allied Digestive Health (PE-backed MSO)(Est.)Access Now
20Atlanta Gastroenterology Associates (duplicate?)123Access Now

    How Many Gastroenterology Physician Group Practices Are There?

    Ampliz Healthcare reports 1,541 active gastroenterology physician group practices in the US. Importantly, this refers to legal entities—it doesn’t count every clinic location or hospital-employed GI physician. Many of these groups manage multiple clinics, offering broader patient coverage.

    Why Focus on the Largest GI Groups?

    1. High-impact purchasing: Large practices conduct bulk purchases of scope equipment, ERP systems, imaging platforms, and supplies.
    2. Centralized decision nodes: Instead of targeting dozens of clinics, you can engage a single executive team for multi-location contracts.
    3. Scalable adoption: Approved solutions can roll out regionally or nationally.
    4. Consolidation trends: M&A activity continues at fever pitch: >130 GI group acquisitions since 2016, accounting for roughly 90% of transaction volume.

    Challenges in Finding Decision-Makers

    Despite their appeal, large GI groups pose several outreach challenges:

    • Opaque org structures: Post‑acquisition MSOs often centralize purchasing but mask who holds procurement authority.
    • Internal gatekeeping: Executive assistants and procurement teams filter out unsolicited vendor outreach.
    • Data fragmentation: Publicly available info on physician count, specialties, and locations is often incomplete or outdated.
    • Competition saturation: Many vendors vie for limited procurement cycles, making differentiation tough.
    • Disjointed contact points: Each group may have a different contact channel—some use physician recruiters, others corporate sales, or director-level procurement.
    • Compliance scrutiny: Healthcare vendors must adhere to privacy and contractual regulations, adding complexity to engagement.

    Marketing to GI Physician Groups Using Ampliz

    Ampliz provides curated healthcare data intelligence, enabling focused and compliant outreach to GI group practices. Here’s how:

    1. Targeted segmentation
      Access verified data on practice size, physician specialties, decision-makers (CEO, CMO, Director of Supply Chain), locations, and affiliations.
    2. Contact accuracy
      Ampliz enriches contact data—direct emails, phone numbers, LinkedIn—all verified to reduce bounce rates and improve open/click-through metrics.
    3. Customization at scale
      Use data filters to isolate large GI groups by size, geography, and organizational structure for customized campaigns.
    4. Compliance-first
      Ampliz ensures contacts are sourced with GDPR, HIPAA, and CCPA considerations in mind, safeguarding outreach legality.
    5. Insight-driven timing
      Monitor practice changes (mergers, expansions) to time pitches around new service implementations or capital investment windows.

    Conclusion & Total US Count

    • 1,541 active gastroenterology physician group practices exist in the U.S.
    • The Top 20 GI groups employ hundreds of physicians, with top practices exceeding 550 providers.
    • These groups are prime targets due to centralized purchasing, extensive procurement cycles, and high-value infrastructure needs.

    Reaching Them for Marketing Your Healthcare Products & Services

    Using Ampliz’s healthcare database platform, you can:

    • Identify and build campaigns aimed at C-level leaders in large GI groups.
    • Leverage accurate phone and email data to cut through gatekeeping and reach decision-makers directly.
    • Use segmentation to send tailored product messages—for example, targeting groups above 200 physicians for capital-intensive equipment.
    • Align outreach with major practice events: acquisitions, expansions, or new clinic rollouts.
    • Ensure compliance at scale, enabling scalable and repeatable outreach.

    Marketing to gastroenterology physician groups is critical their centralized buying power, high procedure volume, and networked structures make them ideal for impactful campaigns. But reaching the right people demands precision data and timing. Ampliz healthcare data intelligence gives you that precision—helping you connect with the correct stakeholder at the right time, with the right message.