Introduction
Gastroenterology is among the fastest-growing specialties in U.S. healthcare. With over 1,500 active gastroenterology physician group practices operating across the country, these groups are hubs for delivering endoscopy, diagnostic, treatment, and specialist care for GI diseases.
Why focus on the largest practices? These groups—such as Texas Digestive Disease Consultants and Gastro Health—operate hundreds of clinicians across multiple states. Targeting such large-scale organizations enables healthcare vendors to secure high-volume contracts, foster strategic partnerships, and streamline sales and marketing efforts into centralized physician networks.
In this post, we explore the 10 largest GI group practices by headcount, delve into the main challenges in accessing decision-makers, and discuss how Ampliz healthcare data intelligence can empower effective marketing outreach.
Top 10 Largest Gastroenterology Physician Group Practices in the US
| Rank | Group Name | Physicians | Data Set |
|---|---|---|---|
| 1 | Comprehensive Breast Care PLLC | 779 | Access Now |
| 2 | Southern California Permanente Medical Group | 386 | Access Now |
| 3 | Pain Control Associates LLC | 117 | Access Now |
| 4 | South Louisiana Medical Associates | 75 | Access Now |
| 5 | Mowery Clinic LLC | 42 | Access Now |
| 6 | Bryn Mawr Medical Specialists Association | 38 | Access Now |
| 7 | White Wilson Medical Center PA | 34 | Access Now |
| 8 | Radiology Associates of Tallahassee PA | 31 | Access Now |
| 9 | Minnesota Gastroenterology (MN) | 29 | Access Now |
| 10 | BSA Amarillo Diagnostic Clinic Inc | 27 | Access Now |
- Data is from the Ampliz Healthcare Data Intelligence product. The number of Physicians represents only those listed as “active” in our database as of October 2025. Data accessed October 2025.
How Many Gastroenterology Physician Group Practices Are There?
Ampliz Healthcare reports 1,541 active gastroenterology physician group practices in the US. Importantly, this refers to legal entities—it doesn’t count every clinic location or hospital-employed GI physician. Many of these groups manage multiple clinics, offering broader patient coverage.
Why Focus on the Largest GI Groups?
- High-impact purchasing: Large practices conduct bulk purchases of scope equipment, ERP systems, imaging platforms, and supplies.
- Centralized decision nodes: Instead of targeting dozens of clinics, you can engage a single executive team for multi-location contracts.
- Scalable adoption: Approved solutions can roll out regionally or nationally.
- Consolidation trends: M&A activity continues at fever pitch: >130 GI group acquisitions since 2016, accounting for roughly 90% of transaction volume.
Challenges in Finding Decision-Makers
Despite their appeal, large GI groups pose several outreach challenges:
- Opaque org structures: Post‑acquisition MSOs often centralize purchasing but mask who holds procurement authority.
- Internal gatekeeping: Executive assistants and procurement teams filter out unsolicited vendor outreach.
- Data fragmentation: Publicly available info on physician count, specialties, and locations is often incomplete or outdated.
- Competition saturation: Many vendors vie for limited procurement cycles, making differentiation tough.
- Disjointed contact points: Each group may have a different contact channel—some use physician recruiters, others corporate sales, or director-level procurement.
- Compliance scrutiny: Healthcare vendors must adhere to privacy and contractual regulations, adding complexity to engagement.
Marketing to GI Physician Groups Using Ampliz
Ampliz provides curated healthcare data intelligence, enabling focused and compliant outreach to GI group practices. Here’s how:
- Targeted segmentation
Access verified data on practice size, physician specialties, decision-makers (CEO, CMO, Director of Supply Chain), locations, and affiliations. - Contact accuracy
Ampliz enriches contact data—direct emails, phone numbers, LinkedIn—all verified to reduce bounce rates and improve open/click-through metrics. - Customization at scale
Use data filters to isolate large GI groups by size, geography, and organizational structure for customized campaigns. - Compliance-first
Ampliz ensures contacts are sourced with GDPR, HIPAA, and CCPA considerations in mind, safeguarding outreach legality. - Insight-driven timing
Monitor practice changes (mergers, expansions) to time pitches around new service implementations or capital investment windows.
Conclusion & Total US Count
- As per Ampliz database 396 active gastroenterology physician group practices exist in the U.S.
- The Top 10 GI groups employ hundreds of physicians, with top practices exceeding 550 providers.
- These groups are prime targets due to centralized purchasing, extensive procurement cycles, and high-value infrastructure needs.
Reaching Them for Marketing Your Healthcare Products & Services
Using Ampliz’s healthcare database platform, you can:
- Identify and build campaigns aimed at C-level leaders in large GI groups.
- Leverage accurate phone and email data to cut through gatekeeping and reach decision-makers directly.
- Use segmentation to send tailored product messages—for example, targeting groups above 200 physicians for capital-intensive equipment.
- Align outreach with major practice events: acquisitions, expansions, or new clinic rollouts.
- Ensure compliance at scale, enabling scalable and repeatable outreach.
Marketing to gastroenterology physician groups is critical their centralized buying power, high procedure volume, and networked structures make them ideal for impactful campaigns. But reaching the right people demands precision data and timing. Ampliz healthcare data intelligence gives you that precision—helping you connect with the correct stakeholder at the right time, with the right message.
