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Peptinov is a biotechonology company based in Paris and founded by Prof. Jean-François Zagury to develop innovative anti-cytoki ...ne therapeutics to treat chronic inflammatory diseases.
Cytokines are major messenger proteins of the immune system and their overproduction is involved in the pathogenesis of several chronic inflammatory diseases (such as rheumatoid arthritis or systemic sclerosis).
Peptinov’s high potential R&D pipeline uses the tools of bioinformatics and molecular modelling to develop innovative therapeutic strategies targeting cytokines, along two axes: vaccines and small molecule inhibitors.
1. Peptinov’s vaccine project aims at developing a breakthrough treatment against chronic inflammatory diseases through tailored peptide-based vaccines targeting cytokines. Peptinov’s strategy is to induce the production of anti-cytokine antibodies directly by the organism of the patient, through immunizations against carefully selected, highly immunogenic peptide sequences.
2. Peptinov's small molecule inhibitor project using the tools of ‘drug design’, which is an innovative approach based on the in silico virtual screening of chemo-libraries (1 million compounds) in order to accelerate the selection of viable hit compounds.
Peptinov’s value proposition is built on its unique capability to develop anti-cytokine products in the current pharmaceutical markets with its advanced technological proprietary platform.Show more