Top 20 Largest Academic Medical Centers in the US

Top 20 Largest Academic Medical Centers in the US
Last updated on July 13th, 2026
Academic Medical Centers (AMCs) are at the forefront of medical education, research, and patient care in the United States. These institutions not only train future healthcare professionals but also drive innovations that shape the future of medicine. For healthcare marketers, understanding the landscape of AMCs is crucial for effective engagement and outreach.
According to the American Hospital Association, there are approximately 6,093 hospitals in the US. Among these, nearly 1,700 are teaching hospitals, with roughly 300 classified as major teaching hospitals or academic medical centers.
Top 20 Largest Academic Medical Centers in the US
The following table lists the top 20 largest AMCs based on the number of interns and residents:
| Rank | Academic Medical Center | City | State | Interns & Residents | Data Set |
|---|---|---|---|---|---|
| 1 | NewYork-Presbyterian Weill Cornell Medical Center | New York | NY | 1,945 | Access Now |
| 2 | Tisch Hospital | New York | NY | 1,333 | Access Now |
| 3 | University Hospital (University of Michigan Medical School) | Ann Arbor | MI | 1,040 | Access Now |
| 4 | Cleveland Clinic Main Campus | Cleveland | OH | 934 | Access Now |
| 5 | Yale New Haven Hospital | New Haven | CT | 915 | Access Now |
| 6 | The Johns Hopkins Hospital | Baltimore | MD | 913 | Access Now |
| 7 | Massachusetts General Hospital | Boston | MA | 1,051 | Access Now |
| 8 | UCSF Medical Center | San Francisco | CA | 796 | Access Now |
| 9 | Vanderbilt University Medical Center | Nashville | TN | 584 | Access Now |
| 10 | UC Davis Medical Center | Sacramento | CA | 646 | Access Now |
| 11 | University of Iowa Hospitals & Clinics | Iowa City | IA | 684 | Access Now |
| 12 | University Hospital (University of Virginia) | Charlottesville | VA | 683 | Access Now |
| 13 | UChicago Medicine Mitchell Hospital | Chicago | IL | 680 | Access Now |
| 14 | Atrium Health Wake Forest Baptist Medical Center | Winston Salem | NC | 675 | Access Now |
| 15 | University of Texas Health Science Center at Houston | Houston | TX | 1,077 | Access Now |
| 16 | Mayo Clinic Hospital – Saint Marys Campus | Rochester | MN | 1,157 | Access Now |
| 17 | UAB Hospital | Birmingham | AL | 1,157 | Access Now |
| 18 | Ohio State University Wexner Medical Center | Columbus | OH | 1,089 | Access Now |
| 19 | University Hospitals Cleveland Medical Center | Cleveland | OH | 1,032 | Access Now |
| 20 | Jackson Memorial Hospital | Miami | FL | 689 | Access Now |
Understanding the Scale of Academic Medical Centers in the US
The United States hosts approximately 300 major teaching hospitals or academic medical centers. These institutions are integral to the healthcare system, offering advanced patient care, conducting groundbreaking research, and educating the next generation of medical professionals.
Reaching Academic Medical Centers with Ampliz
Marketing healthcare products and services to AMCs requires a strategic approach, given their complex structures and decision-making processes. Ampliz offers healthcare data intelligence solutions that can enhance your marketing efforts by providing:
- Comprehensive Contact Data: Access to verified contact information of key decision-makers within AMCs.
- Institutional Insights: Detailed profiles of AMCs, including specialties, research focus areas, and procurement processes.
- Market Segmentation: Ability to segment AMCs based on various criteria such as size, location, and specialty areas.
Utilizing Ampliz’s data intelligence can lead to more targeted marketing campaigns, improved engagement rates, and ultimately, better ROI.
Importance of Marketing to Academic Medical Centers
AMCs are often early adopters of innovative healthcare solutions and set trends that influence the broader medical community. By successfully marketing to these centers, companies can:
- Establish Credibility: Association with reputable AMCs can enhance brand reputation.
- Drive Adoption: Products and services adopted by AMCs are more likely to be accepted by other healthcare institutions.
- Gain Feedback: Collaborating with AMCs can provide valuable insights for product improvement and innovation.
In conclusion, understanding and effectively engaging with the largest academic medical centers in the U.S. is vital for healthcare marketers. Leveraging tools like Ampliz’s healthcare data platform can streamline this process, leading to successful partnerships and advancements in healthcare delivery.

V. Subramanyam
Head of Product at Ampliz | Healthcare Data & GTM Intelligence Expert
V. Subramanyam is the Head of Product at Ampliz, where he leads the strategy and development of healthcare data intelligence solutions that help sales, marketing, recruiting, and commercial teams identify and engage healthcare decision-makers across the United States.
With extensive experience in product management, healthcare data, B2B SaaS, GTM strategy, and sales intelligence, he focuses on building products that simplify healthcare prospecting through accurate physician, hospital, executive, and healthcare organization data. His work emphasizes data quality, enrichment, and AI-powered workflows that enable organizations to make faster, data-driven decisions.
Connect with Him:
- LinkedIn: https://www.linkedin.com/in/vsubramanyam
- Company: https://www.ampliz.com
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