Pain management physician groups play a critical role in diagnosing, treating, and supporting patients experiencing acute and chronic pain. These specialized practices—often led by anesthesiologists, physiatrists, and interventional pain specialists—rely on advanced diagnostic equipment, interventional procedures, and patient monitoring systems to deliver high-quality care.

For medical device manufacturers, pharmaceutical firms, digital health vendors, and clinical service providers, targeting these groups is a high-potential strategy. Compared to hospitals, physician groups often have centralized decision-making, streamlined procurement, and high patient volumes—making them ideal for product adoption and long-term partnerships.

In this comprehensive guide, we’ll:

  1. Rank and profile the top 20 largest pain management physicians groups practices in the U.S.
  2. Quantify the number of active pain management practices nationwide.
  3. Discuss the challenges in identifying decision-makers.
  4. Explain how Ampliz’s healthcare data intelligence can enhance marketing efforts.

Top 20 Largest Pain Management Physician Group Practices

RankGroup PracticeState(s)# PhysiciansDataset
1National Spine & Pain CentersMD, NC, NY, VA, WV, etc.147Access Now
2Advanced Pain CareTX35Access Now
3Coastal Spine & Pain CenterFL29Access Now
4Physician Partners of AmericaFL27Access Now
5Florida Pain Relief GroupFL26Access Now
6Commonwealth Pain & Spine AssociatesKY22Access Now
7Relievus (formerly Advanced Spine & Pain LLC)NJ21Access Now
8Center for Pain ManagementIN20Access Now
9Pain Treatment Centers of AmericaAR19Access Now
10Vein Institute & Pain Centers of America (VIP Medical Group)NY19Access Now
11Center for Interventional Pain & SpineDE16Access Now
12Southeast Pain & Spine CareNC15Access Now
13Vista HealthcareUT15Access Now
14PRC Alliance Pain Relief CentersFL13Access Now
15Pain Management Centers of AmericaIN13Access Now
16Michigan Pain Consultants PCMI13Access Now
17Precision Spine Care (Charles R Gordon MD PA)TX13Access Now
18Alliance Spine and Pain CentersGA13Access Now
19Jacksonville Spine & Pain CenterFL12Access Now
20Central Texas Pain Center South (Pain Specialists of America)TX11Access Now

How Many Pain Management Physician Group Practices Are in the US?

According to the same Ampliz study, there are 955 active pain management physician group practices in the US as of July 2024. Note that each group may oversee multiple clinic locations, further expanding their national presence.

Challenges in Finding Pain Management Group Decision-Makers

Engaging effectively with these groups requires overcoming several hurdles:

  1. Decentralized Organizational Structures
    Some groups operate across multiple states or regions, with purchasing decisions managed at both corporate and local levels—making it hard to know who to approach.
  2. Dual Decision-Making Roles
    Clinical directors or practice administrators may hold the purchasing power, while physicians influence clinical evaluations—requiring a multi-pronged outreach strategy.
  3. Sparse Public Data
    Leadership and contact info are often buried in NPI databases, state filings, or behind subscription-based platforms like Ampliz -a barrier for new entrants.
  4. Complex Purchasing Pathways
    Big groups may use GPOs, value analysis committees, or regional committees, all with varying processes and requirements.
  5. Regulatory & Privacy Constraints
    Compliance with HIPAA and other regulations limits data sharing, requiring modern B2B intelligence tools to navigate securely.

Marketing to Pain Management Groups via Ampliz

Why Target Pain Management Physician Groups?

  • High-volume and high-value procurement
    These groups invest in devices (e.g., nerve stimulators, ultrasound), medications, consumables, EMR software, and clinical analytics.
  • Stable, centralized relationships
    Large groups with multiple clinics value long-term, strategic vendor partnerships.
  • Interventional focus
    Many use advanced interventional treatments—perfect targets for innovative medical devices and digital solutions.

How Ampliz Helps Marketers Reach Them

  1. Curated Contact Intelligence
    Gain verified emails and phone numbers for group leaders—clinical directors, admin execs, and procurement heads.
  2. Organizational Hierarchies
    Discover reporting lines: who reports to whom, who approves budgets and contracts.
  3. Firmographics & Technographics
    Know the group’s size, locations, equipment used, and affiliations—ideal for personalized outreach.
  4. Decision-Maker Identification
    Segment lists by decision-making role and tailor outreach to clinicians vs. administrators.
  5. Compliance-Ready Prospecting
    Data sourced and maintained in line with HIPAA, TCPA, GDPR—ideal for email campaigns or ABM outreach.
  6. Monitor Changes
    Get alerts when groups merge, open new clinics, or add services—stay ahead of buying windows.

How to Reach Them — Step by Step

  1. Shortlist targets
    Use firmographic filters to identify groups by size, location, specialty.
  2. Obtain key contacts
    Export verified emails of clinical and administrative leads.
  3. Multi-channel campaign
    Deploy an Omnichannel strategy: email for initial outreach, phone for follow-ups, LinkedIn for executive alerts.
  4. Personalize your message
    Reference their practice’s profile (e.g., “As the 2nd-largest group in TX…”), and focus on solutions for interventional pain management.
  5. Engage with valuable content
    Share case studies that showcase ROI or improved outcomes specifically for groups like theirs.
  6. Nurture & convert
    Host webinars, join forums, co-develop clinical studies—move from awareness to partnership.

Conclusion

There are 955 active pain management physician group practices in the U.S., with the largest—national groups like National Spine & Pain Centers (147 physicians)—driving substantial procurement on equipment, medications, and technology.

Given their centralized decision-making and operational scale, targeting these groups offers tremendous B2B marketing potential. However, identifying and engaging the right stakeholders is challenging due to decentralized decision structure, privacy regulations, and lack of publicly available data.

By leveraging Ampliz healthcare data intelligence, you can reliably build prospect lists with verified decision-maker contacts, firmographic and technographic insights, and organization charts. This allows for hyper-targeted, compliant outreach campaigns—significantly improving your chances of securing long-term partnerships with these high-value practices.

Call to Action

If you’re seeking to penetrate the pain management specialty, Ampliz offers the data and tools to connect with the right people at the right time. Reach out today to request a tailored list of top pain management physician group decision-makers and fuel your next growth campaign.

Let me know if you’d like assistance in refining outreach scripts, ideating campaign messaging, or analyzing specific group profiles!