Heart disease continues to be a leading cause of death in the United States, and for many with end-stage heart failure, a heart transplant is the only viable option. As a life-saving procedure, heart transplants require the utmost expertise, infrastructure, and long-term care. That’s why patients and their families seek out the top US hospitals for heart transplants institutions that consistently demonstrate excellence in outcomes, innovation, and patient support.

In this article, we’ll explore the best hospitals for heart transplants in the US, what makes them leaders in cardiac transplant care, and how you can connect with their decision-makers using Ampliz Healthcare Data Intelligence.

Understanding Heart Transplants and Their Growing Need

A heart transplant is a surgical procedure in which a diseased heart is replaced with a healthy one from a deceased donor. This complex operation is reserved for patients with advanced heart failure who have exhausted other medical or surgical treatments.

Key Stats:

  • According to UNOS (United Network for Organ Sharing), over 3,500 heart transplants are performed annually in the U.S.
  • The 1-year survival rate for heart transplant recipients is nearly 90%, thanks to advancements in surgical techniques and post-operative care.
  • Demand for donor hearts continues to exceed supply, leading to long waitlist times and strict eligibility criteria.

What Makes a Heart Transplant Center the Best?

Not all transplant hospitals are the same. The top heart transplant hospitals in the US consistently show:

  • High transplant volumes
  • Superior patient survival rates
  • Advanced multidisciplinary cardiac care teams
  • Access to cutting-edge technology and research
  • Efficient organ procurement and allocation systems

Additionally, these hospitals often run comprehensive heart failure and transplant programs, making them ideal for both surgery and long-term care.

Top 20 Hospitals Performing Heart Transplants in the US

Below is a list of the top heart transplant centers in the US, based on transplant volume, survival outcomes, and national recognition:

Hospital NameLocationAnnual Heart Transplants1-Year Survival RateSpecialty ProgramDataSet
Cleveland ClinicCleveland, OH120+94%Advanced Heart Failure and Transplant CtrAccess Now
Cedars-Sinai Medical CenterLos Angeles, CA100+93%Smidt Heart InstituteAccess Now
Mayo ClinicRochester, MN100+95%Transplant CenterAccess Now
NewYork-Presbyterian/ColumbiaNew York, NY90+92%Center for Advanced Cardiac CareAccess Now
Vanderbilt University Medical CenterNashville, TN85+93%Vanderbilt Heart & Vascular InstituteAccess Now
Baylor University Medical CenterDallas, TX80+91%Baylor Scott & White Heart HospitalAccess Now
University of Pennsylvania (Penn)Philadelphia, PA75+90%Penn Heart and Vascular CenterAccess Now
Duke University HospitalDurham, NC70+92%Duke Heart Transplant ProgramAccess Now
Massachusetts General HospitalBoston, MA65+91%Corrigan Minehan Heart CenterAccess Now
Stanford Health CareStanford, CA60+92%Stanford Cardiothoracic Transplant ProgramAccess Now
Houston Methodist HospitalHouston, TX60+90%J.C. Walter Jr. Transplant CenterAccess Now
Northwestern Memorial HospitalChicago, IL55+89%Bluhm Cardiovascular InstituteAccess Now
University of Michigan HospitalsAnn Arbor, MI55+91%Frankel Cardiovascular CenterAccess Now
University of Florida HealthGainesville, FL50+90%UF Health Shands Heart Transplant ProgramAccess Now
University of Utah HealthSalt Lake City, UT45+90%Intermountain Heart InstituteAccess Now
Barnes-Jewish HospitalSt. Louis, MO45+89%Washington University Heart TransplantAccess Now
Ochsner Medical CenterNew Orleans, LA40+88%Ochsner Heart and Vascular InstituteAccess Now
Emory University HospitalAtlanta, GA40+90%Emory Heart and Vascular CenterAccess Now
UC San Diego HealthSan Diego, CA35+91%UCSD Heart Transplant ProgramAccess Now
UPMC PresbyterianPittsburgh, PA30+90%UPMC Heart Transplant ProgramAccess Now

Why These Hospitals Are Leaders in Cardiac Transplant

What sets these hospitals apart isn’t just volume—it’s quality of care, technology, and experience.

Common Success Factors:

  • High-volume experience leads to greater surgical precision and better outcomes.
  • Multidisciplinary teams (cardiologists, surgeons, anesthesiologists, transplant coordinators).
  • Participation in clinical trials and cutting-edge research.
  • Robust follow-up and outpatient transplant services.

For instance, Cedars-Sinai’s Smidt Heart Institute is known for performing more adult heart transplants than any other U.S. hospital, while Cleveland Clinic is frequently ranked #1 in cardiac care nationwide.

How to Choose the Right Heart Transplant Hospital

Choosing where to undergo a heart transplant is a deeply personal and logistical decision.

Key Factors to Consider:

  • Proximity to hospital (important for pre- and post-op visits)
  • Insurance coverage
  • Waitlist time and organ availability
  • Hospital’s transplant volume and success rate
  • Availability of support services (rehab, counseling, nutrition)

Some hospitals may offer remote evaluations or referrals from local cardiologists, making access easier even if you live far from a top transplant center.

Marketing to Heart Transplant Hospitals: Why It Matters

Heart transplant hospitals are not only centers of clinical excellence but also valuable B2B healthcare audiences for:

  • Medical device companies (e.g., LVADs, monitoring devices)
  • Pharma firms (immunosuppressants, post-transplant therapies)
  • Healthcare IT providers (EHR, care coordination platforms)
  • Patient support service vendors (remote monitoring, mental health)

However, reaching the right decision-makers such as transplant surgeons, program directors, and transplant coordinators—can be challenging without verified data.

How Ampliz Helps You Connect With the Right People

Ampliz Healthcare Data platform is your strategic partner in identifying and connecting with high-value contacts across these top heart transplant hospitals.

Key Benefits:

  • Access 2,000+ verified contacts from top cardiac transplant hospitals
  • Detailed profiles including emails, phone numbers, LinkedIn, and job titles
  • Target decision-makers like Chief of Transplant Surgery, Transplant Program Director, Heart Failure Specialist, and CMOs
  • Filters for location, NPI, specialty, hospital size, revenue

Whether you’re a medtech marketer or pharma sales leader, Ampliz gives you the edge to tailor your message to the right person, at the right time.

Conclusion

Heart transplants are complex, life-saving procedures requiring a team of experts and a facility that ranks among the best. The top US hospitals performing heart transplants stand out for their excellence in care, innovation, and results. Whether you’re a patient researching care options or a healthcare company targeting these institutions, it’s vital to know who the leaders are.

And with platforms like Ampliz, you gain the data-driven insight needed to connect directly with the decision-makers driving transplant excellence.