Top 20 Largest Surgery Physician Groups in the United States

Last updated on May 13th, 2026

The United States healthcare system is home to thousands of surgical practices, but only a select few command the scale, specialization, and institutional influence to be recognized as the largest surgery physician groups in the US. Whether you are a healthcare marketer, medical device sales representative, pharmaceutical professional, or healthcare recruiter, knowing which surgical groups dominate each region and specialty is critical to building effective outreach strategies.

Finding the right contact information email addresses, phone numbers, hospital affiliations, and locations can be a monumental task, especially considering the complexity of healthcare organizations, the fragmented nature of medical practices, and the confidentiality rules that govern patient and provider data.

This guide provides a comprehensive, up-to-date list of surgery physician groups in the US, ranked by physician count, along with specialty breakdowns, geographic distribution, and actionable guidance on how to connect with decision-makers within these organizations.

What Is a Surgery Physician Group?

A surgery physician group is an organized medical practice or network of surgeons and surgical specialists who operate under a shared administrative and clinical structure. These groups may be affiliated with academic medical centers, hospital systems, or independent medical organizations.

Surgery physician groups commonly include the following surgical specialties:

• General Surgery
• Orthopedic Surgery
• Neurosurgery
• Cardiovascular and Cardiothoracic Surgery
• Plastic and Reconstructive Surgery
• Surgical Oncology
• Pediatric Surgery
• Urological Surgery

The size of a surgery physician group is typically measured by the number of actively practicing physicians, geographic reach, volume of surgical procedures performed annually, and breadth of subspecialties covered.

Top 20 Largest Surgery Physician Groups in the United States

Here we lists 20 largest surgery physician groups in the United States, organized by physician count as of 2026. These groups represent the most influential surgical networks across the country, spanning major academic medical centers, integrated health systems, and specialized surgical organizations.

This is where Ampliz Healthcare Intelligence comes in. Real time and updated data. Accessed on May 2026

How Are Surgery Physician Groups Ranked?

Ranking surgery physician groups by size involves several key criteria. Understanding these factors helps healthcare professionals and marketers assess the true scale and market influence of each group.

1. Total Physician Count

The primary metric used in this list is the number of physicians actively practicing within the group. Groups with 1,000 or more physicians are considered large-scale surgical networks.

2. Multi-Specialty Coverage

Groups that cover multiple surgical disciplines, including orthopedics, cardiac surgery, and neurosurgery, carry more institutional weight than single-specialty practices.

3. Geographic Footprint

Multi-location surgical groups operating across cities, counties, or states have a broader patient and referral network, directly influencing their market ranking.

4. Academic & Hospital Affiliation

Groups affiliated with top-ranked academic medical centers, such as UCSF, Mayo Clinic, or Brigham and Women’s Hospital, benefit from research programs, teaching facilities, and enhanced credibility.

Breakdown by Surgical Specialty

Among the top 20 largest surgery physician groups, five major specialty categories are represented:

• Multi-Specialty Surgery: Groups such as Mayo Clinic Arizona (2,012 physicians), UCSF Medical Center (1,182 physicians), and the University of Chicago Medical Center (1,113 physicians) offer the widest range of surgical disciplines.
• Orthopedic Surgery: Orthopaedics Indianapolis Inc. (172 physicians) and CNOS PC (74 physicians) are prominent orthopedic surgery groups in their respective states.
• Neurosurgery: Texas is home to two specialized neurosurgical groups Neurosurgical Group of Texas LLP (65 physicians) and Neurosurgical Associates of San Antonio, P.A. (20 physicians).
• Pediatric Surgery: The Nemours Foundation (343 physicians) based in Delaware is a leading pediatric surgical group serving children across multiple states.
• Plastic & Reconstructive Surgery: OSU Plastic Surgery LLC (38 physicians) in Ohio focuses exclusively on plastic and reconstructive procedures.

Geographic Distribution of Major Surgery Groups in US

The largest surgery physician groups are not uniformly distributed across the United States. The following states host the greatest concentration of large surgical groups:

• California: Three of the top 20 groups are based in California, including UCSF Medical Center, Alameda Health System, and Southern California Permanente Medical Group, reflecting the state’s large population and advanced healthcare infrastructure.
• Massachusetts: Brigham and Women’s Physicians Organization (1,398 physicians) and Lahey Clinic Inc. (384 physicians) anchor the Northeast surgical market.
• Colorado: Both University Physicians Incorporated (1,656 physicians) and Colorado Permanente Medical Group (1,109 physicians) are headquartered in Colorado.
• Texas: Two specialized neurosurgical groups operate out of Texas, serving a fast-growing patient population.
• New York: NYU’s medical group and Kaleida Health are two prominent New York-based surgical networks.

Why Healthcare Marketers Target Surgery Physician Groups?

For healthcare sales and marketing professionals, surgery physician groups represent high-value target accounts for several reasons:

• High Procurement Authority: Large surgical groups make significant purchasing decisions for surgical devices, implants, equipment, and pharmaceuticals.
• Concentrated Access: Reaching one group can provide access to hundreds of surgeons and decision-makers simultaneously.
• Repeat Business Potential: Surgical groups engage in recurring procurement cycles, making them long-term revenue opportunities.
• Referral Network Influence: Large groups also influence patient referrals across the broader healthcare ecosystem, affecting downstream purchasing behavior.

How to Access Surgery Physician Group Contact Data?

Finding accurate, HIPAA-compliant contact data for surgery physician groups is one of the most common challenges in healthcare marketing. Traditional methods, such as manual directory searches or cold outreach, are time-consuming and often yield outdated results.

Platforms like Ampliz Healthcare Intelligence provide verified, real-time contact data for surgery physician groups across the US, including:

• Direct physician email addresses and office phone numbers
• Hospital and practice affiliations
• Specialty and subspecialty classifications
• Geographic filters by city, state, or ZIP code
• Practice size and physician count data
• NPI (National Provider Identifier) numbers for verification

This enables healthcare marketers and sales teams to build highly targeted outreach campaigns, reduce prospecting time, and improve engagement rates significantly.

Use Cases: Healthcare Sales, Marketing & Recruiting

Medical Device & Equipment Sales

Sales representatives targeting orthopedic and cardiovascular surgical groups can use physician group data to identify the right contacts, understand practice volume, and personalize their outreach based on specialty and hospital affiliation.

Pharmaceutical Marketing

Pharmaceutical companies promoting surgical anesthetics, wound care products, or post-operative medications benefit from direct access to surgeon contact lists segmented by specialty and geography.

Healthcare Recruiting

Recruiting firms placing surgeons can use physician group data to map open positions, identify high-growth practices, and target surgeons affiliated with top-ranked groups.

Health Technology Sales

Companies selling surgical robotics, electronic health records (EHR), or imaging solutions can identify large physician groups as enterprise-level prospects with significant purchasing budgets.

Frequently Asked Questions:

Q1: What is the largest surgery physician group in the United States?

A: Mayo Clinic Arizona is one of the largest surgery physician groups in the United States, with over 2,012 physicians. It is closely followed by University Physicians Incorporated in Colorado (1,656 physicians) and Brigham and Women’s Physicians Organization in Massachusetts (1,398 physicians).

Q2: How many physicians does UCSF Medical Center have?

A: UCSF Medical Center’s surgery physician group includes approximately 1,182 physicians, making it one of the largest surgical networks in California and the broader United States.

Q3: What types of surgery do the largest physician groups specialize in?

A: The largest surgery physician groups in the US cover a wide range of specialties, including multi-specialty surgery, orthopedic surgery physician groups, neurosurgery physician groups, cardiothoracic surgery, plastic and reconstructive surgery, pediatric surgery, and surgical oncology.

Q4: How do I find contact information for surgery physician groups?

A: You can find verified contact information for surgery physician groups through healthcare data platforms such as Ampliz Healthcare Intelligence, which provides physician email addresses, phone numbers, hospital affiliations, NPI numbers, and specialty data updated in real time.

Q5: Which states have the most large surgery physician groups?

A: California, Massachusetts, Colorado, New York, and Texas have the highest concentration of large surgery physician groups in the United States, driven by population density, academic medical centers, and integrated health systems.

Q6: Are surgery physician group contact lists HIPAA compliant?

A: Reputable healthcare data providers ensure that surgical group marketing data are compliant with HIPAA and other applicable privacy regulations. These lists contain professional contact information for physicians, not patient data, and are sourced ethically from public and licensed databases.

Q7: What is the difference between a surgery physician group and a hospital?

A: A surgery physician group is a network or practice organization of surgeons operating under shared administrative structures. A hospital is a licensed medical facility where surgeries and treatments are performed. Physician groups may be affiliated with hospitals but are distinct legal and operational entities.

Q8: How are surgery physician groups ranked by size?

A: Top surgical groups United States are typically ranked by total physician count, geographic footprint, number of surgical specialties offered, annual procedure volume, and affiliation with academic or hospital systems.

Q9: Can healthcare marketers legally reach out to surgery physician groups?

A: Yes. Healthcare marketers can legally contact physicians and surgery groups for B2B sales and marketing purposes, provided the outreach adheres to applicable regulations such as CAN-SPAM, TCPA, and any state-specific commercial communication laws. Patient data must never be used for marketing.

Conclusion

Understanding the landscape of the largest surgical practices US is essential for anyone working in healthcare marketing, medical device sales, pharmaceutical outreach, or surgical recruiting. The top 20 groups identified in this guide represent thousands of surgeons across multiple specialties and geographies, offering significant market opportunity for healthcare businesses.

Accessing accurate, verified, and up-to-date contact data for these groups is the key differentiator between inefficient outreach and high-converting campaigns. Ampliz the reputed healthcare database providers delivering surgery physician group contact data that is HIPAA-compliant, regularly updated, and filterable by specialty, location, and practice size.

Ready to connect with the largest surgery physician groups in the US? Access verified contact data on Ampliz Healthcare Intelligence today.

Subbu

V. Subramanyam
Head of Product at Ampliz | Growth-focused B2B Leader

V. Subramanyam is a Head of Product at Ampliz with a strong focus on driving growth and innovation. As the Head of Product at Ampliz, I leads the development and strategic direction of cutting-edge solutions that empower businesses to leverage high-quality healthcare data for better decision-making. With years of experience in product management and leadership, I have deep industry knowledge with a customer-centric approach to deliver value-driven products that accelerate business success. And I am passionate about using data intelligence to transform businesses and create impactful outcomes.