{"id":3536,"date":"2025-04-08T12:13:13","date_gmt":"2025-04-08T12:13:13","guid":{"rendered":"https:\/\/www.ampliz.com\/resources\/largest-physician-groups-in-south-carolina\/"},"modified":"2026-03-30T08:32:34","modified_gmt":"2026-03-30T08:32:34","slug":"largest-physician-groups-in-south-carolina","status":"publish","type":"post","link":"https:\/\/www.ampliz.com\/resources\/largest-physician-groups-in-south-carolina\/","title":{"rendered":"Top 20 Largest Physician Groups in South Carolina"},"content":{"rendered":"

Last updated on March 30th, 2026<\/p>\n

Why Target Physician Groups in South Carolina?<\/strong><\/h2>\n\n\n\n

South Carolina\u2019s healthcare landscape is rapidly expanding, with physician groups playing a critical role in delivering care across primary, specialty, and surgical services. These medical groups\u2014ranging from multi-specialty giants to focused specialists\u2014are influential stakeholders in healthcare purchasing decisions, clinical collaborations, and technology adoption.<\/p>\n\n\n\n

For healthcare marketers, service providers, and medtech vendors, these physician groups are prime opportunities for product adoption, partnerships, and growth. However, breaking into these organizations can be a challenge without the right data and strategies. That\u2019s where Ampliz Healthcare Intelligence comes in\u2014an advanced platform designed to help you identify, connect with, and convert key decision-makers within physician groups across the United States, including South Carolina.<\/p>\n\n\n\n

We list the top 20 largest physician groups in South Carolina, explain how to reach them effectively, and show you how Ampliz can accelerate your marketing success in this space.<\/p>\n\n\n\n

Top 20 Largest Physician Groups in South Carolina<\/strong><\/h2>\n\n\n\n

Here\u2019s a curated list of the largest physician groups operating in South Carolina based on physician count, specialties, regional presence, and service volume:<\/p>\n\n\n\n

#<\/th>Physician Group Name<\/th>Location<\/th>Specialty Focus<\/th>Estimated Physicians<\/th>Website \/ Contact<\/th><\/tr><\/thead>
1<\/td>Prisma Health Medical Group<\/td>Greenville, SC<\/td>Multi-specialty<\/td>1,200+<\/td>Signup Now<\/a><\/td><\/tr>
2<\/td>MUSC Physicians<\/td>Charleston, SC<\/td>Academic Multi-specialty<\/td>900+<\/td>Signup Now<\/a><\/td><\/tr>
3<\/td>Roper St. Francis Physician Partners<\/td>Charleston, SC<\/td>Multi-specialty<\/td>600+<\/td>Signup Now<\/a><\/td><\/tr>
4<\/td>Bon Secours St. Francis Medical Group<\/td>Greenville, SC<\/td>Multi-specialty<\/td>400+<\/td>Signup Now<\/a><\/td><\/tr>
5<\/td>Lexington Medical Center Physician Network<\/td>West Columbia, SC<\/td>Multi-specialty<\/td>500+<\/td>Signup Now<\/a><\/td><\/tr>
6<\/td>McLeod Physician Associates<\/td>Florence, SC<\/td>Multi-specialty<\/td>400+<\/td>Signup Now<\/a><\/td><\/tr>
7<\/td>AnMed Health Medical Group<\/td>Anderson, SC<\/td>Multi-specialty<\/td>300+<\/td>Signup Now<\/a><\/td><\/tr>
8<\/td>Spartanburg Regional Medical Group<\/td>Spartanburg, SC<\/td>Multi-specialty<\/td>500+<\/td>Signup Now<\/a><\/td><\/tr>
9<\/td>Tidelands Health Group<\/td>Murrells Inlet, SC<\/td>Primary & Specialty Care<\/td>200+<\/td>Signup Now<\/a><\/td><\/tr>
10<\/td>Carolina Health Centers, Inc.<\/td>Greenwood, SC<\/td>Family Practice<\/td>100+<\/td>Signup Now<\/a><\/td><\/tr>
11<\/td>Doctors Care<\/td>Columbia, SC<\/td>Urgent Care<\/td>200+<\/td>Signup Now<\/a><\/td><\/tr>
12<\/td>Colonial Family Practice<\/td>Sumter, SC<\/td>Family Medicine<\/td>50+<\/td>Signup Now<\/a><\/td><\/tr>
13<\/td>Self Regional Healthcare<\/td>Greenwood, SC<\/td>Multi-specialty<\/td>300+<\/td>Signup Now<\/a><\/td><\/tr>
14<\/td>Conway Medical Center Physician Network<\/td>Conway, SC<\/td>Multi-specialty<\/td>150+<\/td>Signup Now<\/a><\/td><\/tr>
15<\/td>Beaufort Memorial Physician Partners<\/td>Beaufort, SC<\/td>Multi-specialty<\/td>120+<\/td>Signup Now<\/a><\/td><\/tr>
16<\/td>Pee Dee Health Care<\/td>Florence, SC<\/td>Primary & Urgent Care<\/td>80+<\/td>Signup Now<\/a><\/td><\/tr>
17<\/td>Regional Medical Center Physicians<\/td>Orangeburg, SC<\/td>Internal Medicine, OB\/GYN<\/td>70+<\/td>Signup Now<\/a><\/td><\/tr>
18<\/td>HopeHealth<\/td>Florence, SC<\/td>Community Health, Primary<\/td>100+<\/td>Signup Now<\/a><\/td><\/tr>
19<\/td>Carolina Pines Medical Group<\/td>Hartsville, SC<\/td>Primary & Specialty Care<\/td>60+<\/td>Signup Now<\/a><\/td><\/tr>
20<\/td>Carolina Family Medicine<\/td>Charleston, SC<\/td>Family Medicine<\/td>50+<\/td>Signup Now<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

How to Reach South Carolina Physician Groups for Marketing?<\/strong><\/h2>\n\n\n\n

Breaking into a physician group requires more than just sending a cold email. Here\u2019s a multi-pronged approach to reach, engage, and convert them:<\/p>\n\n\n\n

1. Use Data-Driven Targeting<\/strong><\/h3>\n\n\n\n

Use accurate healthcare provider data to segment your outreach based on:<\/p>\n\n\n\n